About Genestra Brands Citrigen 90 Capsules
Echinacea and flavonoid combination
- Echinacea angustifolia is traditionally used in Herbal Medicine to help relieve the symptoms of upper respiratory tract infections and to help relieve sore throats
- Provides 1000 mg of Echinacea root per daily dose
- Includes 480 mg of grapefruit fruit extract (9600 mg Dried Equivalent, standardized to 45% bioflavonoids) per daily dose
- 80 mg of green tea leaf and 40 mg of peppermint leaf per daily dose
Citrigen is a source of Echinacea angustifolia, which is traditionally used to help decrease symptoms of upper respiratory tract infections (URTI) and sore throats. Echinacea reduces the release of pro-inflammatory cytokines from immune cells and invading pathogens, including IL-6 and TNF-α, which contribute to symptoms of URTI.1 Adults who consumed 100 mg of Echinacea root extract daily demonstrated significantly decreased pro-inflammatory IL-6 and TNF-α mRNA levels after four weeks of supplementation.2 Echinacea also stimulates the phagocytic activity of immune cells and decreases the survival of bacteria.1,3 Research demonstrates that echinacea can decrease the secretion of mucin, reducing the amount of mucous produced during infections.3 TRPV1 is a pain receptor present in sensory tissues that integrates pain and inflammatory responses.4 Desensitization of this receptor can block the transmission pain, and receptor agonists may therefore exert analgesic effects.4 In vitro research demonstrates that Echinacea angustifolia root is 10 times more effective at activating the TRPV1 receptor than capsaicin, a strong ligand for the receptor.4 As echinacea can activate and desensitize this receptor, it helps reduce pain associated with infections, including sore throats.4
REFERENCES
1. Woelkart, K, Bauer, R. Planta Med. 2007; 73(7): 615-623.
2. Hudson, JB. Journal of Biomedicine and Biotechnology. 2012; 2012: 769896.
3. Dapas, B, Dall’Acqua, S, Bulla, R, Agostinis, C, Perissutti, B, Invernizzi, S, Voinovich, D, Grassi, G. Phytomedicine. 2014; 21: 1406_1410.
4. Birt, DF, Widrlechner, MP, LaLone, CA, Wu, L, Bae, J, Solco, AKS, Kraus, GA, Murphy, PA, Wurtele, ES, Leng, Q, Hebert, SC, Maury, WJ, Price, JP. Am J Clin Nutr. 2008; 87(2): 488S-492S.
Echinacea and flavonoid combination
- Echinacea angustifolia is traditionally used in Herbal Medicine to help relieve the symptoms of upper respiratory tract infections and to help relieve sore throats
- Provides 1000 mg of Echinacea root per daily dose
- Includes 480 mg of grapefruit fruit extract (9600 mg Dried Equivalent, standardized to 45% bioflavonoids) per daily dose
- 80 mg of green tea leaf and 40 mg of peppermint leaf per daily dose
Citrigen is a source of Echinacea angustifolia, which is traditionally used to help decrease symptoms of upper respiratory tract infections (URTI) and sore throats. Echinacea reduces the release of pro-inflammatory cytokines from immune cells and invading pathogens, including IL-6 and TNF-α, which contribute to symptoms of URTI.1 Adults who consumed 100 mg of Echinacea root extract daily demonstrated significantly decreased pro-inflammatory IL-6 and TNF-α mRNA levels after four weeks of supplementation.2 Echinacea also stimulates the phagocytic activity of immune cells and decreases the survival of bacteria.1,3 Research demonstrates that echinacea can decrease the secretion of mucin, reducing the amount of mucous produced during infections.3 TRPV1 is a pain receptor present in sensory tissues that integrates pain and inflammatory responses.4 Desensitization of this receptor can block the transmission pain, and receptor agonists may therefore exert analgesic effects.4 In vitro research demonstrates that Echinacea angustifolia root is 10 times more effective at activating the TRPV1 receptor than capsaicin, a strong ligand for the receptor.4 As echinacea can activate and desensitize this receptor, it helps reduce pain associated with infections, including sore throats.4
REFERENCES
1. Woelkart, K, Bauer, R. Planta Med. 2007; 73(7): 615-623.
2. Hudson, JB. Journal of Biomedicine and Biotechnology. 2012; 2012: 769896.
3. Dapas, B, Dall’Acqua, S, Bulla, R, Agostinis, C, Perissutti, B, Invernizzi, S, Voinovich, D, Grassi, G. Phytomedicine. 2014; 21: 1406_1410.
4. Birt, DF, Widrlechner, MP, LaLone, CA, Wu, L, Bae, J, Solco, AKS, Kraus, GA, Murphy, PA, Wurtele, ES, Leng, Q, Hebert, SC, Maury, WJ, Price, JP. Am J Clin Nutr. 2008; 87(2): 488S-492S.
EACH CAPSULE CONTAINS: Echinacea (Echinacea angustifolia) Root. . . . . . . . . . . . . . . . . . . . . . . . . . . . .250 mg Grapefruit (Citrus paradisi) Fruit Extract (20:1). . . . . . . . . . . . . . . . . . . . . . . 120 mg (45% Bioflavonoids / 2400 mg Dried Equivalent) Green Tea (Camellia sinensis) Leaf. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 20 mg Peppermint (Mentha piperita) Leaf. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 10 mg
Non-Medicinal Ingredients: Hypromellose, cellulose, magnesium silicate, magnesium stearate
Recommended Adult Dose: Take two capsules two times daily with meals or as recommended by your healthcare practitioner. For use beyond eight weeks, consult your healthcare practitioner.
Genestra Brands Citrigen 90 Capsules Disclaimer
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Occasionally, some items may be shipped with alternate packaging that has been recently updated by the supplier or manufacturer. It's important to note that while packaging may change, the ingredients usually remain the same. We always advise you to read labels, warnings, and product directions before use. Please do not solely rely on the information provided by Healthy Planet Canada.
Probiotics Disclaimer:
Our probiotics are stored in our warehouse under refrigeration to guarantee quality and maintain optimal potency. Additionally, we include a FREE ice pack with probiotic shipments. Although the product may not arrive cold, the ice pack helps in preserving a cooler temperature during transit. We recommend taking into account potential weekend or holiday delays when placing your order. For example, it's best to order on a weekday and avoid ordering on Fridays, Saturdays, or during holidays
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