About Xymogen MedCaps DPO 120c
MedCaps DPO
- Made In Canada
- Helps to support liver function
- Provides a source of antioxidants
The term "Dual-Phase Optimizers" refers to those substances with the ability to simultaneously influence and "optimize" the activity of certain phase I and phase II detoxification enzyme systems. Optimizers generally upregulate or induce phase II enzymes; however, optimizing phase I enzymes may mean downregulating them, without totally inhibiting them, when they are too high. Dual-phase optimizers may further balance the phases of detoxification by supporting antioxidant defense systems and binding free radicals formed between the two phases.
Examples of dual-phase optimizers in MedCaps DPO include ellagic acid from pomegranate, catechins from green tea extract, and glucosinolates from watercress powder. Ellagic acid induces phase II enzymes at the gene level and ensures these are not over-induced by modulation of CYP1A (cytochrome P450 1A) activities. In addition, ellagic acid can bind directly to DNA to protect it and can also bind directly to some toxic substances to promote their excretion. The catechins in green tea support antioxidant activity and may bind directly to toxic substances as well, performing dual functions during detoxification. When toxic substances are encountered, catechins modulate detoxification by limiting phase I enzyme production.[3] Glucosinolates are precursors to isothiocyanates. Watercress, in particular, is metabolized by gut flora into phenylethyl isothiocyanate (PEITC), which, like the other ingredients above, can selectively inhibit phase I enzymes and induce the activities of phase II enzymes.
Liver detoxification is further supported with the inclusion of silymarin (milk thistle seed extract), artichoke leaf extract, and alpha-lipoic acid, all of which are selected for their hepatoprotective properties. These key players also promote glutathione production and assist with antioxidant protection.
Additional ingredients in this formula are present to support vital phase II detoxification pathways. Key ingredients that support methylation include methylsulfonylmethane (MSM), methylcobalamin (B12), and 5-methyltetrahydrofolate (folate). 5-methyltetrahydrofolate (5-MTHF) is present as Quatrefolic (a stable, bioavailable form of folate) to support methylation, energy generation, and phase I and phase II activity. Calcium D-glucarate has been added to support glucuronidation. Sulfate donors sodium sulfate and N-acetyl-cysteine (NAC) are especially important in cases of heavy-metal burden because they support glutathione production and the sulfation pathway.
MedCaps DPO is designed to be part of a comprehensive detoxification protocol that includes adequate high-quality protein, carbohydrates, fats, and fiber. The resulting combination provides micronutrients to support the active phases of detoxification and macronutrients to support energy production, amino acid conjugation, and elimination.
MedCaps DPO
- Made In Canada
- Helps to support liver function
- Provides a source of antioxidants
The term "Dual-Phase Optimizers" refers to those substances with the ability to simultaneously influence and "optimize" the activity of certain phase I and phase II detoxification enzyme systems. Optimizers generally upregulate or induce phase II enzymes; however, optimizing phase I enzymes may mean downregulating them, without totally inhibiting them, when they are too high. Dual-phase optimizers may further balance the phases of detoxification by supporting antioxidant defense systems and binding free radicals formed between the two phases.
Examples of dual-phase optimizers in MedCaps DPO include ellagic acid from pomegranate, catechins from green tea extract, and glucosinolates from watercress powder. Ellagic acid induces phase II enzymes at the gene level and ensures these are not over-induced by modulation of CYP1A (cytochrome P450 1A) activities. In addition, ellagic acid can bind directly to DNA to protect it and can also bind directly to some toxic substances to promote their excretion. The catechins in green tea support antioxidant activity and may bind directly to toxic substances as well, performing dual functions during detoxification. When toxic substances are encountered, catechins modulate detoxification by limiting phase I enzyme production.[3] Glucosinolates are precursors to isothiocyanates. Watercress, in particular, is metabolized by gut flora into phenylethyl isothiocyanate (PEITC), which, like the other ingredients above, can selectively inhibit phase I enzymes and induce the activities of phase II enzymes.
Liver detoxification is further supported with the inclusion of silymarin (milk thistle seed extract), artichoke leaf extract, and alpha-lipoic acid, all of which are selected for their hepatoprotective properties. These key players also promote glutathione production and assist with antioxidant protection.
Additional ingredients in this formula are present to support vital phase II detoxification pathways. Key ingredients that support methylation include methylsulfonylmethane (MSM), methylcobalamin (B12), and 5-methyltetrahydrofolate (folate). 5-methyltetrahydrofolate (5-MTHF) is present as Quatrefolic (a stable, bioavailable form of folate) to support methylation, energy generation, and phase I and phase II activity. Calcium D-glucarate has been added to support glucuronidation. Sulfate donors sodium sulfate and N-acetyl-cysteine (NAC) are especially important in cases of heavy-metal burden because they support glutathione production and the sulfation pathway.
MedCaps DPO is designed to be part of a comprehensive detoxification protocol that includes adequate high-quality protein, carbohydrates, fats, and fiber. The resulting combination provides micronutrients to support the active phases of detoxification and macronutrients to support energy production, amino acid conjugation, and elimination.
| (per vegetarian capsule) | |
| Vitamin B6 (Pyridoxal-5-phosphate) | 12.5 mg |
| Folate (6S)-5-Methyltetrahydrofolic acid, glucosamine salt) | 100 mcg |
| Vitamin B12 (Methylcobalamin) | 50 mcg |
| Artichoke Aqueous Extract (Cynara scolymus) (leaf)(15:1) | 150 mg |
| Watercress (Nasturtium officinale) (leaf).. | 125 mg |
| Milk Thistle Extract (Silybum marianum) (seed) (80% silymarin). | 62.625 mg |
| Pomegranate Extract (Punica granatum) (fruit) (40% ellagic acid).. | 62.5 mg |
| DL-alpha-Lipoic acid | 50 mg |
| N-Acetyl-L-Cysteine | 50 mg |
| Green Tea Aqueous Extract (Camellia sinensis) (leaf) (80% polyphenols, 60% catechins, 30% EGCG, 6% caffeine) | 46.875 mg |
| Methylsulfonylmethane (MSM) | 25 mg |
| Calcium D-Glucarate | 25 mg |
Recommended Dose
Adults: Take 2 capsules twice daily with food, or as directed by your healthcare practitioner.
Consult a healthcare practitioner prior to use if you are pregnant or breastfeeding or have kidney stones, gallstones, diabetes, or iron deficiency. Consult a healthcare practitioner if symptoms persist or worsen. Do not use if you are taking nitroglycerin or antibiotics, or are allergic to plants of the Asteracea/Com- positae/Daisy family or have a bile duct obstruction. If allergy occurs, discontinue use.
If you experience sweating, paleness, chills, headache, dizziness and/or confusion, discontinue use and consult a healthcare practitioner. Stop use if you develop symptoms of liver trouble such as yellowing of the skin/eyes (jaundice), stomach pain, dark urine, sweating, nausea, unusual tiredness and/or loss of appetite and consult a healthcare practitioner. Rare, unpredictable cases of liver injury associated with green tea extract-containing products have been reported.
Do not use if tamper seal is damaged.
Keep out of reach of children. Store in a cool dry place.
Xymogen MedCaps DPO 120c Disclaimer
Nature's Source is committed to ensuring the complete and absolute accuracy of product images and information on our website. However, please be aware that there may be pending updates to packaging or ingredients due to manufacturing changes.
Occasionally, some items may be shipped with alternate packaging that has been recently updated by the supplier or manufacturer. It's important to note that while packaging may change, the ingredients usually remain the same. We always advise you to read labels, warnings, and product directions before use. Please do not solely rely on the information provided by Healthy Planet Canada.
Probiotics Disclaimer:
Our probiotics are stored in our warehouse under refrigeration to guarantee quality and maintain optimal potency. Additionally, we include a FREE ice pack with probiotic shipments. Although the product may not arrive cold, the ice pack helps in preserving a cooler temperature during transit. We recommend taking into account potential weekend or holiday delays when placing your order. For example, it's best to order on a weekday and avoid ordering on Fridays, Saturdays, or during holidays
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