N-Acetylcysteine (NAC) is a precursor to glutathione synthesis and also acts on its own to reduce the effects of reactive oxygen species. NAC also has mycolytic properties and decreases the viscosity of lung secretions. NAC has been shown by studies to have a protective effect on the liver. NAC has been used to manage acetaminophen overdose, due to its ability to enhance hepatic and mitochondrial levels of glutathione and by supporting the mitochondrial energy metabolism. NAC is also an effective treatment for influenza. Research has shown NAC treatment can improve recovery from influenza by improving host defense mechanisms and its antioxidant effect against the oxidative stress associated with viral infections.
