Folate is a vitamin with many essential roles in health. Low levels of folate during pregnancy are associated with neural tube defects, such as spina bifida. Insufficient folate levels are also associated with cardiovascular disease, colon cancer, AlzheimerÃ¢â‚¬Å¡Ã¢â‚¬Å¾s disease, depression and megaloblastic anemia. Less severe but still unpleasant symptoms of low folate status can include weakness, fatigue, and shortness of breath.
Heart Health, Cancer and Other Roles
Folate has an essential role in DNA synthesis, protein metabolism, cognitive function and red blood cell production. Supplemental folate has been associated with a reduced risk of colorectal cancer. It is also required in methylation cycles, which are an important part of many biological pathways. One of these pathways is the conversion of homocysteine into useful compounds. High levels of homocysteine (and low levels of folate) are associated with problems in the cardiovascular system.
Your BodyÃ¢â‚¬Å¡Ã¢â‚¬Å¾s Preference
Biofolate is the form of folate that is produced in the body, and is the natural, preferred form for performing its biological roles. A sufficient amount of vitamin B12, according to the Recommended Dietary Allowance, has been added since folate can mask a vitamin B12 deficiency. AORÃ¢â‚¬Å¡Ã¢â‚¬Å¾s Biofolate provides an effective supplemental form to maintain this essential nutrient at optimal levels.