Currency

FREE EXPEDITED SHIPPING $59.99 *  |  FLYER

Shopping Cart

BioClinic Naturals EstroVantage EM 90 v-caps

In stock
SKU
44336
CA$43.00
  • IGF-1 has a known pathogenic role in cancer, increasing growth of existing cancer cells. Lycopene supplementation decrease IGF-1 by 25%.7
  • In a 34 patient randomized controlled trial foods enriched with bioactive compounds, including rosemary extract (Rosemarinus officinalis), were found to be a promising adjuvant therapy in advanced breast cancer patients8
  • Green tea polyphenols inhibit the proliferation of breast cancer cellsin vivoandin vitro9

    EstroVantage EM Product Specifications

Benefits
  • IGF-1 has a known pathogenic role in cancer, increasing growth of existing cancer cells. Lycopene supplementation decrease IGF-1 by 25%.7
  • In a 34 patient randomized controlled trial foods enriched with bioactive compounds, including rosemary extract (Rosemarinus officinalis), were found to be a promising adjuvant therapy in advanced breast cancer patients8
  • Green tea polyphenols inhibit the proliferation of breast cancer cellsin vivoandin vitro9
  • Silymarin can down-regulate gene products involved in the proliferation of tumour cells (cyclin D1, EGFR, COX-2, TGF-beta, IGF-IR), invasion (MMP-9), angiogenesis (VEGF) and metastasis (adhesion molecules)10
  • Curcumin inhibits human breast cancer cell growth by mediating certain signalling cascades including the modulation of the NF-ºB signalling pathway11
  • Sulforaphane can inhibit the expression of estrogen receptor alpha (ERalpha) protein in MCF-7 cells, inhibiting proliferation and down-regulating hormone receptor expression12
  • Suitable for vegetarians/vegans
Feature Summary

In general, estrogen can be divided into several biochemically distinct hormones: estrone (E1), estradiol (E2), estriol (E3), and 17²-estradiol.1In premenopausal women, estrogen is enzymatically converted to several specific estrogen metabolites including 2-hydroxyestrone (2-OHE1), 2-hydroxyestradiol (2-OHE2), 4-hydroxyestrone (4-OHE1), 4-hydroxyestradiol (4-OHE2) and 16-hydroxyestrone (16-OHE1). Both 16-OHE1 and 2-OHE have contrasting biological activities at the cellular level with 16-OHE1 being an estrogen agonist and proliferative, while 2-OHE is an estrogen antagonist and antiproliferative.2As such, an increased ratio 2-OHE:16-OHE1 is associated with a reduced risk of invasive breast cancer risk in premenopausal women.3Several natural products found in EstroVantage EM support this latter concept including DIM, and indole 3 carbinol (I3C). A human study has confirmed that daily supplementation with 300 mg of I3C daily for 12 weeks significantly increased the 2-OH-estrone: estriol metabolite ratio without notable adverse events.4Other compounds in EstroVantage EM, including calcium-d-glucarate, inhibit beta-glucoronidase activity, allowing for the excretion of estrogen before reabsorption.5It is estimated that a 4% calcium glucarate supplemented diet inhibits beta-glucuronidase activity by 70%.6

EstroVantage EM Product Specifications

More Information
Brand BIOCLINIC NATURALS
Age Group Unknown
Write Your Own Review
Only registered users can write reviews. Please Sign in or create an account
Frequently Bought Together
  • Total price