Douglas Laboratories Prim Royal 60 v-caps - Discontinued

Prim Royal contains 500 mg of oil of organic, cold-pressed evening primrose oil providing 40 mg of the nutritionally important gamma linolenic acid (GLA) and 350 mg of the essential fatty acid, linoleic acid. These liquid filled two piece capsules are not made from gelatin, making this product suitable for vegetarians.

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SKU
41293

Discontinued

Prim Royal contains 500 mg of oil of organic, cold-pressed evening primrose oil providing 40 mg of the nutritionally important gamma linolenic acid (GLA) and 350 mg of the essential fatty acid, linoleic acid. These liquid filled two piece capsules are not made from gelatin, making this product suitable for vegetarians.

Diets in developed countries are often rich in animal products which deliver large amounts of saturated fatty acids and the polyunsaturated arachidonic acid (20:4 omega-6). Intakes of the essential linoleic acid (18:2 omega-6) can be low in people who do not regularly consume vegetable oils in their diets. Arachidonic acid is a precursor for pro-inflammatory immune mediators, the 2-series prostaglandins, e.g. prostaglandin E2, the leukocyte chemotactic metabolite, leukotriene B4, and platelet aggregating thromboxane A2. 

Thromboxane A2 has been implicated in the pathogenesis of coronary vascular disease, as it is not only a potent platelet aggregator, but also an effective vasoconstrictor. Although gamma-linolenic acid (18:3 omega-6) is a precursor of arachidonic acid, higher levels of dietary GLA actually compete with arachidonic acid, and may help down regulate the formation of excessive levels of proinflammatory 2-series prostaglandins and other immune mediators. Dietary supplementation with GLA has been suggested to be clinically effective in reducing the signs and symptoms of immune dysfunction. It has also been clinically associated with improvement of behavioral and physical problems, including premenstrual syndrome, learning disability, mental disturbance, weakness, poor coordination, and vision impairment. Recent studies suggest that dietary GLA can prevent the deficit on sciatic nerve conduction velocity (NCV) induced by poor glucose control. 

Although dietary GLA supplementation did not significantly influence the fatty acid composition of nerve membrane phospholipids, it was suggested that GLAs effect was due to its modulation of levels of vasodilatory prostaglandins. Evening primrose oil is recognized as an excellent source of both GLA as well as the essential linoleic acid. Therefore, regular supplementation with evening primrose oil may be beneficial for people consuming diets high in animal foods and low in unprocessed vegetable oils.

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